Pharmaceutical industry

A faster remedy for batch management and documentation

Smart-Bio Manufacturing: next-generation biopharma processes

Data-driven processes can make bio API production not only smarter, but more agile and reliable as well.

Continuously improving productivity

Trends Digitalization changes all areas of life: The way we stay informed, the way we travel, the way we buy things – and the way we manufacture products. The pace of innovation and the ability to disrupt are becoming key success factors in global competition. The pharmaceutical industry is no exception. Smarter products and experiences are challenging the way drugs have been produced until now – and at the same time, they open up new business opportunities.

With our proven, digital solutions, you can take efficiency, quality and productivity to the next level in your pharmaceutical value chain.

Research and development, primary processing, secondary processing – every stage of the processes used in the pharmaceutical industry has its own specific demands.

How can the pharmaceutical industry transfer emerging technologies into an effective process? One answer is in an efficient tech transfer from R&D to recipes for production.

Our integrated digital solutions can pave the way to lean production and right-first-time quality in primary processing.

From the receipt of materials and goods to the formulation of drugs and product packaging: Our sophisticated technological concepts provide you with quality, flexibility and agility.

Taking the fast lane to integrated operations: Solutions for digitalization from product to production

To address the challenges of future R&D and production requirements, the pharmaceutical industries needs solutions that help make operations more flexible and productive. Digitalization can help cut time to market, and that further improve quality by supporting right-first-time production through data integrity and consistency across the value chain. Additionally, digitalization benefits the industry by providing data integration, analysis and simulation capabilities and will help streamline today's operations and open up business opportunities for the future.

Accelerating time to market with integrated engineering and operations

Digitalization is a vital instrument in picking up speed during a crucial phase of your value chain: the transfer of a new drug from R&D to production. With our solutions for integrated engineering and operation, you can streamline process development and maturity and increase production flexibility and asset utilization at the same time – by ensuring data consistency across the entire lifecycle.

With COMOS, Siemens delivers a comprehensive software solution for the optimal integration of engineering and operation. Using a global, single data platform ensures consistent documentation and highly efficient plant operation from the planning stage onward. Combined with SIMATIC PCS 7, we can extend this integrated approach to the automation level, providing a central data management environment for plant engineers and operators. Your benefit: reduced time to market at lower costs and with improved quality.

Agile, efficient and flexible processes with digital solutions

Drugs are increasingly produced in highly specific, individual formulations – often in amounts of less than 100 dosages. Consequently, batch changes must be very fast and flexible, and modular plant designs require a high level of production flexibility to serve an increasingly personalized demand for pharmaceutical products. With SIMATIC IT eBR, Siemens offers a software solution for electronic master batch record (eBR) management that enables native integration between the manufacturing execution system (MES), the MOM portfolio and the distributed control system (DCS) using SIMATIC PCS 7 and SIMATIC BATCH. SIMATIC IT eBR expedites the design, execution, review and release of master batch records (MBR) and electronic batch records (eBR). It also enhances MBR design flexibility by providing all the master information from SIMATIC BATCH to the MES design tool. With our SIMATIC IT Preactor production planning and scheduling software products, you can improve the synchronization of your manufacturing processes, giving you greater visibility and control to increase utilization and on-time delivery while reducing inventory levels and waste. Our SIPAT solution for process analytical technology integrates the PAT tools with the process control system and enables the chemometrical calculations in real time to achieve real time release – cutting time to market significantly. And finally, our SIMIT simulation software will help you test and assess the impact of changes on production in a virtual environment without risks for process and equipment. It will speed up process changes through virtual commissioning and advanced training for your staff – for a better process right from the start.

Better decisions thanks to smarter data

With markets becoming more volatile and innovation driving production, it is increasingly vital to use the right tools to make the right decision for your operations: Where do I have the capabilities to squeeze in this extra batch? How can I produce it with the optimum resources? Digitalization can provide the tools that help answer these questions right here and now.

At the plant and process level, our modular SIMATIC WinCC monitoring and operation system provides a detailed insight into current and scheduled processes and networks seamlessly with our manufacturing IT. It also tracks all operations for documentation and review. Our XHQ Operations Intelligence platform aggregates, relates and presents operational and business data in real-time to improve enterprise performance. Through XHQ, you have a single and coherent view of information for all operations in your pharmaceutical production units. This enables real-time performance management and decision support.

Faster time-to-market Win the race against time with our solutions for product quality and compliance that follow Good Manufacturing Practice (GMP) guidelines. You benefit from improved efficiency and productivity, and can reach the market faster.

Our products, solutions, and services for Good Manufacturing Practice (GMP) help ensure that your pharmaceutical production processes fully comply with the latest regulations and guidelines.

Learn how the SIPAT software solution allows your company to further develop its processes based on Quality by Design (QbD) and right-first-time testing.

Services Streamline your digitalization projects by utilizing the capabilities and know-how of our service experts.

Digital Services

Use our modular portfolio of data-based services and combine them to suit your individual requirements.

We also provide services to assist with an assessment of your digital maturity, to enable the first steps on a digital strategy.

Digital Services

IT Security

Our coordinated portfolio of solutions especially for the security of industrial facilities.

IT Security

References Already today, automation and digitalization are transforming the pharmaceutical industry. These are just a few examples of what our customers have achieved with our digital solutions.

Pfizer

Germany

Continued excellence

Freiburg in Germany is one of Pfizer's secondary manufacturing hubs
A state-of-the-art IT and automation solution was implemented during an upgrade and expansion project
The solution helps increase quality and efficiency and paves the way to Paperless Manufacturing

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BioNTech

Germany

Personalized medicine

Customization is an important trend in medical technology
Biotechnology company BioNTech specializes in developing personalized cancer vaccines
BioNTech has chosen Siemens as its strategic partner in the field of GMP production

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Julphar

Middle East

Quality of Life, Quality of Product

Fully automated bulk process provides high-quality, affordable products
A SIMATIC PCS 7 system with 11 S7-417s automates the plant, reducing production costs
Siemens automation, expert project management, and customizable after-service solutions ensure that the plant is on target to achieve its production goal of 40 million vials of insulin each year