Digitized production for personalized medicine

The vision of BioNTech is to revolutionize the tumor treatment with medicine tailored specifically for each patient. Discover how our software for digital production brings the vision closer to reality.
The vision

Medicine tailored for the patient

There is barely any other disease as particular as cancer. That is what also makes it so hard to treat. A emerging biotech company believes it is close to a solution – with an approach that considers the genetic profile of each and every patient as well as their condition. The vision of personalised tumor vaccines, however, is blurred by an extremely complex research and production process. Our software helps to bring this vision a little closer to reality.

The future of tumor treatment could emerge from BioNTech AG's Mainz-based research centre. Company founder Prof. Ugur Sahin and his colleagues are hoping that the fruits of their labour will fulfill a long-cherished dream: a treatment that essentially offers each and every patient realistic chances of recovery.  

One of the reasons why such a personalized treatment has not yet successfully been developed lies in the singular nature of cancer diseases. Tumors are created by random gene mutations and not one patient has the same clinical picture. BioNTech's vision is to tailor tumor medicine specifically for these unique clinical pictures. In other words: to apply genetic analysis techniques to identify mutations and to produce a proprietary medication that ultimately mobilises the patient's immune system against the mutant cells.

The fastest way from the lab to practical applications

Until recently, such a procedure would have been destined to fail due to the immense effort required in practise. Only modern digitalization and automation technology allows personalised medicine to be produced in adequate quantities for clinical studies and hence meet the preconditions for a possible market introduction.  

At BioNTech, our software plays a key role: the company uses SIMATIC IT eBR (Electronic Batch Record) to efficiently document every step. This speeds up considerably activities in the lab and guarantees compliance with the strictest statutory provisions. In production BioNTech uses an intelligent planning tool SIMATIC IT Preactor to coordinate all the steps. It allows hundreds of different medicines to be produced in parallel in the shortest possible time.  

This effectively reaches several important milestones along the road to market approval for personalised medicine. The next step is to confirm the efficacy of such vaccines with larger numbers of probands. 

SIMATIC IT in use

A working day in the digital laboratory

The benefits of digitalised documentation and automated planning have been an integral part of BioNTech's everyday lab activities for some time now. Get an idea of the day-to-day work with SIMATIC IT eBR and Preactor in practice.
Customer references

The same result in one second flat

We have enjoyed an ongoing partnership with BioNTech for over two years now, continually facing new challenges and always overcoming them together. Read what they think about the collaboration and our products.